HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fluorotrimethylsilane
FLUOROTRIMETHYLSILANE · TRIMETHYLSILYL FLUORIDE · (CH3)3SiF · fluorotrimethyl-silan · TRIMETHYLFLUOROSILANE · Silane,fluorotrimethyl- · Trimethylfluorosilane99% · Trimethylsilicon fluoride
Identifiers & Physical Properties
| CAS No. | 420-56-4 |
|---|---|
| Molecular formula | C3H9FSi |
| Average molar mass | 92.19 g/mol |
| Monoisotopic mass | 92.04575504 g/mol |
| SMILES | C[Si](C)(C)F |
| InChIKey | CTIKAHQFRQTTAY-UHFFFAOYSA-N |
| PubChem CID | 9869 |
| EC No. | 206-997-0 |
| DTXSID | DTXSID5059959 |
Chemical & Physical Properties
| Topological polar surface area | 0 |
|---|---|
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 1 |
| Rotatable bonds | 0 |
| Heavy atoms | 5 |
| Formal charge | 0 |
| Complexity | 28.4 |
| Chemical classes | Toxic Gases & Vapors -> Fluorosilanes |
| SpringerMaterials Properties | 19F nuclear magnetic resonance spectrum |
| Physical Description | Liquefied gas with a pungent irritating odor[Alfa Aesar MSDS] |
| Melting point | −74 °C(lit.) |
| Boiling point | 16 °C(lit.) |
| Density | 0.793 g/mL at 25 °C(lit.) |
| Flash point | −22 °F |
| Solubility | sol most organic solvents |
| Specific gravity | 0.793 |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 1731132 |
| CAS DataBase Reference | 420-56-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Silane, fluorotrimethyl-(420-56-4) |
| EPA Substance Registry System | Fluorotrimethylsilane (420-56-4) |
| GHS pictogram | GHS02,GHS04,GHS07 |
| Signal word | Danger |
| GHS hazard statements | H224-H280-H315-H319-H335 |
| GHS precautionary statements | P210-P233-P240-P303+P361+P353-P305+P351+P338-P410+P403 |
| Hazard symbols | F+,Xi,F |
| Risk statements (R) | 12-36/37/38 |
| Safety statements (S) | 9-16-26-33 |
| UN transport number | UN 1954 2.1 |
| Water hazard class (WGK) | 3 |
| F | 4.5-9-21 |
| Hazard Note | Flammable |
| TSCA inventory status | TSCA listed |
| Hazard class | 2.1 |
| Customs code | 2931900090 |
Safety & Regulations
| GHS classification | DangerH224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, P410+P403, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazards summary | Hydrolyzed by moisture evolving hydrogen fluorideCauses burnsInhalation may cause corrosive injuries to the respiratory tract and pulmonary edema[Alfa Aesar MSDS] See Methyltrifluorosilane and Difluorodimethylsilane. |
| Hazard Classes and Categories | Flam. Liq. 1 (100%) |
| Exposure control and personal protection | TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016]. |
| Protective Action Criteria (PAC) | 1.0 [ppm]24 [ppm]44 [ppm] |
| Adverse effects | Dermatotoxin - Skin burns. |
| F | 4.5-9-21 |
| Water hazard class (WGK) | 3 |
| TSCA inventory status | TSCA listed |
| UN transport number | UN 1954 2.1 |
| Customs code | 2931900090 |
| Risk statements (R) | 12-36/37/38 |
| Signal word | Danger |
| GHS pictogram | GHS02,GHS04,GHS07 |
| Hazard symbols |
Applications & Uses
Uses
Trimethylfluorosilane is used in the pharmaceutical and chemical industry.
Preparation & Synthesis
Preparation
Trimethylfluorosilane can be prepared from Chlorotrimethylsilane (TMSCl) by direct treatment with Hydrofluoric Acid. It can also be generated in situ by reaction of Ethyl Trimethylsilylacetate (ETSA) and Tetra-n-butylammonium Fluoride (TBAF).