Basic information
- CAS
182439-41-4- Standard SMILES
O=C(NC1CCNCC1)c1ccccc1-c1ccc(C(F)(F)F)cc1- InChIKey
AQANXBKFOZBCIY-UHFFFAOYSA-N- Molecular formula
- C19H19F3N2O
- Average molar mass
- 348.4 g/mol
Names & identifiers
- Preferred name
- N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamide
- IUPAC
- N-piperidin-4-yl-2-[4-(trifluoromethyl)phenyl]benzamide
- English name
- N-(piperidin-4-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide
- Molecular formula
- C19H19F3N2O
- Molecular weight
- 348.36
Names & synonyms
182439-41-4N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamideLomitapide metabolite M1BP7YFS63H2UNII-BP7YFS63H2N-4-Piperidinyl-4'-(trifluoromethyl)(1,1'-biphenyl)-2-carboxamide(1,1'-Biphenyl)-2-carboxamide, N-4-piperidinyl-4'-(trifluoromethyl)-[1,1'-Biphenyl]-2-carboxamide, N-4-piperidinyl-4'-(trifluoromethyl)-RefChem:202045N-(Piperidin-4-yl)-4'-(trifluoromethyl)biphenyl-2-carboxamideN-(PIPERIDIN-4-YL)-4'-(TRIFLUOROMETHYL)-[1,1'-BIPHENYL]-2-CARBOXAMIDEN-piperidin-4-yl-2-[4-(trifluoromethyl)phenyl]benzamide
Show more names
N-4-Piperidinyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamideN-(piperidin-4-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamideethyl)-[1,1'-biphenyl]-2-carboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide
MFCD27978680N-(piperidin-4-yl)-4-(trifluoromethyl)biphenyl-2-carboxamideLomitapide M1SCHEMBL593798orb3218332DB-4034494-(4'-Trifluoromethylbiphenyl-2-carbonylamino)piperidineN-(4-Piperidinyl)-4'-(trifluoromethyl)-2-biphenylcarboxamide
Properties
Computed structural properties
- XLogP
- 3.8
- Topological polar surface area
- 41.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 440
Physicochemical properties
- Boiling point
- 480.8 · 480.8±45.0 °C(Predicted)
- Density
- 1.27 · 1.27±0.1 g/cm3(Predicted)
- storage temp.
- Store at Room Tem.
- pka
- 14.06 · 14.06±0.20(Predicted)
- FDA UNII
- 7 YFS63H2 · BP7YFS63H2
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 303 · H303-H320
- Precautionary statements
- 312 · P312-P264-P305+P351+P338-P337+P313
- HS Code
- 2933399990 · 2933399990
Safety & regulation
Safety data
- hs_code
- 2933399990
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H303-H320
- Precautionary statements
- P312-P264-P305+P351+P338-P337+P313
Chemistry & industry
Applications
UsesN-(Piperidin-4-yl)-4''-(trifluoromethyl)-biphenyl-2-carboxamide is a reagent used in the preparation of lomitapide mesylate crystal forms. Lomitapide mesylate is a microsomal triglyceride transfer protein inhibitor which can lower the level of low density lipoprotein cholesterol in plasma. Lomitapide (L469435) metabolite.
Suppliers12 total
艾琪康医药科技（上海）有限公司13661411401 · [email protected]
北京康派森医药科技有限公司010-010-52878169 15801002657 · [email protected]
海思化医药科技（北京）有限公司010-52980412 · [email protected]
Alfa Chemistry+1-5166625404 · [email protected]
苏州美石生物科技有限公司1173954148q · [email protected]
湖南和众医药科技有限公司027-87614241 3310618156 · [email protected]
艾琪康医药科技（上海）有限公司13512160998; 13512160998 · [email protected]
西安瑞谱源生物技术有限公司18192620610
北京佰康和诺科技有限公司010-57296878 15633144420 · [email protected]
郑州凡尔赛特化工有限公司0371-67991738 13783628208 · [email protected]
艾览（上海）化工科技有限公司400-668-9898 · [email protected]
Related reactions
10 records
Compound notes
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