Methanol → C-[6-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyridin-7-yl]-methylamine

Reaction equation

[BH3:20].[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:26][OH:27].[Cl:1][c:2]1[c:3](-[c:9]2[c:10]([C:18]#[N:19])[cH:11][c:12]3[n:13]([cH:14]2)[cH:15][cH:16][n:17]3)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1>>[Cl:1][c:2]1[c:3](-[c:9]2[c:10]([CH2:18][NH2:19])[cH:11][c:12]3[n:13]([cH:14]2)[cH:15][cH:16][n:17]3)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

Reactant 4

HCID 887Methanol

HCID 6331Borane

HCID 8028Tetrahydrofuran2×

HCID 666590596-(2,4-Dichloro-phenyl)-imidazo[1,2-a]pyridine-7-carbonitrile

Product 1

HCID 24849505C-[6-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyridin-7-yl]-methylamine

Sources & evidence

ORD record: ord-591b822bff3b48e98ad53e00e140f312
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…