Acetate → 4-O-benzyl 2-O-tert-butyl 4-methyl-5-phenylpyrrolidine-2,4-dicarboxylate

HRID 100350

Reaction equation

HRID 100350 reaction equation
[Ag+:44].[C:17]([C:18](=[CH2:19])[CH3:20])(=[O:21])[O:22][CH2:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[C:40]([O-:41])(=[O:42])[CH3:43].[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:37][C:38]#[N:39].[CH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)=[N:8][CH2:9][C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16]>>[CH:1]1([c:2]2[cH:3][cH:4][cH:5][cH:6][cH:7]2)[NH:8][CH:9]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:19][C:18]1([C:17](=[O:21])[O:22][CH2:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[CH3:20]

Participants

7

Reactant 6

HCID 175AcetateHCID 6342AcetonitrileHCID 8471TriethylamineHCID 17236Benzyl methacrylateHCID 104755Silver cationHCID 14506168(E)-tert-butyl 2-(benzylideneamino)acetate

Product 1

HCID 1403858904-O-benzyl 2-O-tert-butyl 4-methyl-5-phenylpyrrolidine-2,4-dicarboxylate

Sources & evidence

ORD record
ord-efb43c20ee7342fb95b16db9dcbe0197
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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