Dimethylformamide → 2-[N-(4-chlorophenyl)-N-(3-methoxybenzyl)amino]-4H-pyrido[3,2-e]-1,3-thiazin-4-one

Reaction equation

[CH3:21][O:22][c:23]1[cH:24][c:25]([CH2:26][Cl:27])[cH:28][cH:29][cH:30]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:6][c:7]2[s:8][c:9]3[c:10]([c:11](=[O:13])[n:12]2)[cH:14][cH:15][cH:16][n:17]3)[cH:18][cH:19]1.[LiH:20].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([N:6]([c:7]2[s:8][c:9]3[c:10]([c:11](=[O:13])[n:12]2)[cH:14][cH:15][cH:16][n:17]3)[CH2:26][c:25]2[cH:24][c:23]([O:22][CH3:21])[cH:30][cH:29][cH:28]2)[cH:18][cH:19]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 699943-Methoxybenzyl chloride

HCID 42920704H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-

HCID 178506917HCID 178506917, compound

Product 1

HCID 154855062-[N-(4-chlorophenyl)-N-(3-methoxybenzyl)amino]-4H-pyrido[3,2-e]-1,3-thiazin-4-one

Sources & evidence

ORD record: ord-7bf2df287df94633963fabba8a8bc155
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…