4-(tert-Butylaminosulphonyl)benzeneboronic acid → 4-(Aminosulphonyl)benzeneboronic acid
Reaction equation
C([NH:5][S:6]([C:9]1[CH:14]=[CH:13][C:12]([B:15]([OH:17])[OH:16])=[CH:11][CH:10]=1)(=[O:8])=[O:7])(C)(C)C>C(O)(C(F)(F)F)=O.CCOCC>[NH2:5][S:6]([C:9]1[CH:10]=[CH:11][C:12]([B:15]([OH:17])[OH:16])=[CH:13][CH:14]=1)(=[O:8])=[O:7]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A solution of 4-t-butylaminosulfonylbenzene boronic acid (500 mg) in TFA (5 mL) was stirred at r.t. for 15 h. The mixture was diluted with ether and the solid material was filtered to provide the title compound.
Workup
- filtrationthe solid material was filtered
Sources & evidence
- ORD record
- ord-07f470340be640ab8eb15f74be1c9dc0
- Source dataset
- uspto-grants-2000_04
- Patent number
- US06046217
Reaction notes
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