2-Methoxybenzaldehyde → alpha-(2-methoxyphenyl)-N-t-butylnitrone

HRID 1003688

Reaction equation

HRID 1003688 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=O.[C:11]([NH:15][OH:16])([CH3:14])([CH3:13])[CH3:12]>>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=[N+:15]([C:11]([CH3:14])([CH3:13])[CH3:12])[O-:16]

Participants

3

Reactant 2

HCID 86582-MethoxybenzaldehydeHCID 98586N-tert-butylhydroxylamine

Product 1

HCID 85447185alpha-(2-methoxyphenyl)-N-t-butylnitrone

Procedure

The title compound was prepared according to the procedure described in Example 7 using 2-methoxybenzaldehyde and N-tert-butylhydroxylamine. The title compound was isolated in 82.9% overall yield as white crystals, m.p. 109.1 ° C. (Rf =0.53 on a silica gel plate using ethyl acetate as the eluant).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-619ea8b4edd344849d580107504db57f
Source dataset
uspto-grants-2000_04
Patent number
US06046232

Linked notes

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