Hydrochloric Acid → HCID 22605443, compound
Reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][N:5]([C:7]2[CH:16]=[CH:15][C:10]([C:11]([O:13]C)=[O:12])=[CH:9][CH:8]=2)[CH:6]=1.[OH-].[Na+].Cl>CO>[CH3:1][C:2]1[N:3]=[CH:4][N:5]([C:7]2[CH:16]=[CH:15][C:10]([C:11]([OH:13])=[O:12])=[CH:9][CH:8]=2)[CH:6]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution (5 ml) of methyl 4-(4-methyl-1H-imidazol-1-yl)benzoate (137 mg, 0.635 mmol) in methanol was added 1M sodium hydroxide (5 ml), and the mixture was stirred at room temperature for 3 hrs. 1M Hydrochloric acid (5 ml) was added to the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was used for the next reaction without purification.
Workup
- customthe solvent was evaporated under reduced pressure
- customThe residue was used for the next reaction without purification
Sources & evidence
- ORD record
- ord-9944bbd18ab2432aaef4b4715d146693
- Source dataset
- uspto-grants-2011_07
- Patent number
- US07973163B2
Reaction notes
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