Butylamine → Phenyl n-butylcarbamate

HRID 1010269

Reaction equation

HRID 1010269 reaction equation
[CH2:1]([NH2:5])[CH2:2][CH2:3][CH3:4].[CH3:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[C:12]([O:15]CC)(=[O:14])C>>[CH2:1]([NH:5][C:12](=[O:14])[O:15][C:8]1[CH:7]=[CH:6][CH:11]=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 3

HCID 8007ButylamineHCID 8058HexaneHCID 8857Ethyl Acetate

Product 1

HCID 97513Phenyl n-butylcarbamateYield 71.97%

Procedure

n-Butylamine (4.9 ml, 50 mmol) was used for the same reaction as in Production Example 310-1, and purification was performed by silica gel column chromatography (hexane:ethyl acetate=4:1) to obtain the title compound (8.11 g, 41.97 mmol, 71.97%) as a colorless oil.

Sources & evidence

ORD record
ord-dd3147b8cc154d93bbe98d5884dd34b1
Source dataset
uspto-grants-2011_07
Patent number
US07973160B2

Linked notes

Loading…