1-Methylpiperazine → 3-Fluoro-N-(4-{[2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]oxy}-1-naphthyl)-5-piperidin-1-ylbenzamide

HRID 101036

Reaction equation

HRID 101036 reaction equation
[CH3:38][N:39]1[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]1.[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][cH:10][c:11]([O:18][c:19]3[n:20][c:21]([S:25]([CH3:26])(=[O:27])=[O:28])[n:22][cH:23][cH:24]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[cH:29][c:30]([N:32]2[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]2)[cH:31]1>>[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][cH:10][c:11]([O:18][c:19]3[n:20][c:21]([N:42]4[CH2:41][CH2:40][N:39]([CH3:38])[CH2:44][CH2:43]4)[n:22][cH:23][cH:24]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[cH:29][c:30]([N:32]2[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]2)[cH:31]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 667379693-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide

Product 1

HCID 595535003-Fluoro-N-(4-{[2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]oxy}-1-naphthyl)-5-piperidin-1-ylbenzamide

Sources & evidence

ORD record
ord-5a7d185427a24cc9b2d88f91e222baff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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