4-Aminobenzyl alcohol → (4-(4-Chloro-5-(trifluoromethyl)pyrimidin-2-ylamino)phenyl)methanol

HRID 101293

Reaction equation

HRID 101293 reaction equation
[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[cH:14][cH:15][c:16]([CH:19]([NH:20][C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH3:28])[cH:17][cH:18]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][OH:35])[cH:36][cH:37]1>>[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[cH:14][cH:15][c:16]([CH2:34][OH:35])[cH:17][cH:18]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]

Participants

3

Reactant 2

HCID 693314-Aminobenzyl alcoholHCID 76611269Tert-butyl 1-(4-(4-chloro-5-(trifluoromethyl)pyrimidin-2-ylamino)phenyl)ethylcarbamate

Product 1

HCID 57584696(4-(4-Chloro-5-(trifluoromethyl)pyrimidin-2-ylamino)phenyl)methanol

Sources & evidence

ORD record
ord-dce2ec02919c434092d82621bc3d744b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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