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3-Iodobenzylamine → 2-Chloro-6-[(3-iodobenzyl)amino]-9-cyclopentenylpurine

HRID 1017321
Notes
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Reaction equation

HRID 1017321 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[C:11]2[CH2:15][CH2:14][CH2:13][CH:12]=2)=[C:4](Cl)[N:3]=1.[I:17][C:18]1[CH:19]=[C:20]([CH:23]=[CH:24][CH:25]=1)[CH2:21][NH2:22]>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[C:11]2[CH2:15][CH2:14][CH2:13][CH:12]=2)=[C:4]([NH:22][CH2:21][C:20]2[CH:23]=[CH:24][CH:25]=[C:18]([I:17])[CH:19]=2)[N:3]=1
ParticipantsProcedureSources & evidenceReaction notes

Participants

4

Reactant 2

HCID 970123-IodobenzylamineHCID 180021022,6-Dichloro-9-cyclopentenylpurine

Product 1

HCID 180017992-Chloro-6-[(3-iodobenzyl)amino]-9-cyclopentenylpurine

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[(3-iodobenzyl)amino]-9-cyclopentenylpurine is prepared from 2,6-dichloro-9-cyclopentenylpurine, 3-iodobenzylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-d383cb28c6d1427990182544b6a6d685
Source dataset
uspto-grants-2002_11
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US06479487B1

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes