Octanoic Acid → Palmitamidopropyl Dimethylamine

HRID 1019310

Reaction equation

HRID 1019310 reaction equation
[C:1]([OH:18])(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[C:19]([OH:32])(=O)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]CC.[C:33]([OH:42])(=O)[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].[CH3:43][N:44]([CH3:49])[CH2:45][CH2:46][CH2:47][NH2:48]>>[C:1]([NH:48][CH2:47][CH2:46][CH2:45][N:44]([CH3:49])[CH3:43])(=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[C:19]([NH:48][CH2:47][CH2:46][CH2:45][N:44]([CH3:49])[CH3:43])(=[O:32])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].[C:33]([NH:48][CH2:47][CH2:46][CH2:45][N:44]([CH3:49])[CH3:43])(=[O:42])[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]

Participants

7

Reactant 4

HCID 379Octanoic AcidHCID 985Palmitic AcidHCID 3893Lauric AcidHCID 7993N,N-Dimethyl-1,3-propanediamine

Product 3

HCID 38313Palmitamidopropyl DimethylamineHCID 89889Caprylamidopropyl dimethylamineHCID 89890Capramidopropyl dimethylamine

Procedure

Hexadecanoic acid, dodecanoic acid or octanoic acid was used instead of octadecanoic acid, and these fatty acids were allowed to react with N,N-dimethyl-1,3-diaminopropane in the same manner as described in Synthesis Example 1 to obtain N-hexadecanoyl-N′,N′-dimethyl-1,3-diaminopropane, N-decanoyl-N′,N′-dimethyl-1,3-diaminopropane and N-octanoyl-N′,N′-dimethyl-1,3-diaminopropane, respectively.

Workup

  1. customas described in Synthesis Example 1

Sources & evidence

ORD record
ord-203466d1ef704337a302cd3f3ff1d232
Source dataset
uspto-grants-2002_11
Patent number
US06486333B1

Linked notes

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