Bromoacetone → tert-butyl [(1S)-2-({6-[6-(2-fluoropropoxy)-1,3-benzoxazol-2-yl]pyridin-3-yl}oxy)-1-methylethyl]carbamate

Reaction equation

O[CH:2]([CH3:32])[CH2:3][O:4][C:5]1[CH:31]=[CH:30][C:8]2[N:9]=[C:10]([C:12]3[N:17]=[CH:16][C:15]([O:18][CH2:19][C@@H:20]([NH:22][C:23](=[O:29])[O:24][C:25]([CH3:28])([CH3:27])[CH3:26])[CH3:21])=[CH:14][CH:13]=3)[O:11][C:7]=2[CH:6]=1.OC1C=CC2N=C(C3N=CC(OC[C@@H](NC(=O)OC(C)(C)C)C)=CC=3)OC=2C=1.BrCC(=O)C.COCCN(S(F)(F)[F:76])CCOC.C(=O)([O-])O.[Na+]>C1(C)C=CC=CC=1>[F:76][CH:2]([CH3:32])[CH2:3][O:4][C:5]1[CH:31]=[CH:30][C:8]2[N:9]=[C:10]([C:12]3[N:17]=[CH:16][C:15]([O:18][CH2:19][C@@H:20]([NH:22][C:23](=[O:29])[O:24][C:25]([CH3:28])([CH3:27])[CH3:26])[CH3:21])=[CH:14][CH:13]=3)[O:11][C:7]=2[CH:6]=1