Hydrazine hydrate (1:1) → HCID 15754479, compound
Reaction equation
[N+:1]([C:4]1[CH:19]=[CH:18][CH:17]=[CH:16][C:5]=1[C:6]([CH:8]1[C:13](=O)[CH2:12][CH2:11][CH2:10][C:9]1=[O:15])=O)([O-:3])=[O:2].O.[NH2:21][NH2:22]>C(O)C>[O:15]=[C:9]1[CH2:10][CH2:11][CH2:12][C:13]2[NH:22][N:21]=[C:6]([C:5]3[CH:16]=[CH:17][CH:18]=[CH:19][C:4]=3[N+:1]([O-:3])=[O:2])[C:8]1=2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
3.2 g (12.2 mmol) of 2-nitrobenzoylcyclohexane-1,3-dione and 0.52 g (12.2 mmol) of hydrazine hydrate (80%) are refluxed for 4 hours in 120 ml of ethanol. The ethanol is subsequently distilled off under reduced pressure, and 80 ml of methanol are added. The solid which precipitates is filtered off with suction and dried in vacuo. 1.41 g (45% of theory) of 4,5,6,7-tetrahydro-4-oxo-3-(2-nitro-phenyl)-1H-indazole of the formula ##STR6## and of melting point 236° C. (decomp.) are obtained.