Dichloromethane → tert-Butyl 4-(6-chloro-2-(methylthio)pyrimidin-4-yl)piperazine-1-carboxylate

HRID 103307

Reaction equation

HRID 103307 reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]1.[CH3:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17].[Cl:1][c:2]1[n:3][c:4]([S:9][CH3:10])[n:5][c:6]([Cl:8])[cH:7]1.[Cl:31][CH2:32][Cl:33]>>[c:2]1([N:28]2[CH2:27][CH2:26][N:25]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[CH2:30][CH2:29]2)[n:3][c:4]([S:9][CH3:10])[n:5][c:6]([Cl:8])[cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 805314,6-Dichloro-2-(methylthio)pyrimidineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 58878061tert-Butyl 4-(6-chloro-2-(methylthio)pyrimidin-4-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-335cd35e53044a81b5c9a62c7832cf11
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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