Tetrahydrofuran → 1-(6-Methoxy-2-naphthyl)-4-(trifluoromethyl)cyclohexanol
Reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:14][CH2:15][CH2:16][CH2:17][Li:18].[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([Br:13])[cH:9][c:10]2[cH:11][cH:12]1.[F:19][C:20]([CH:21]1[CH2:22][CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1)([F:28])[F:29]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([C:24]3([OH:27])[CH2:23][CH2:22][CH:21]([C:20]([F:19])([F:28])[F:29])[CH2:26][CH2:25]3)[cH:9][c:10]2[cH:11][cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-b8afcd6043724748ba504cb9f187347a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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