Dichloromethane → N-(4-bromo-thiophen-2-ylmethyl)-2-chloro-N-isobutyl-benzenesulfonamide

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([CH2:7][NH:8][CH2:9][CH:10]([CH3:11])[CH3:12])[s:5][cH:6]1.[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:13][c:14]1[c:15]([S:20](=[O:21])(=[O:22])[Cl:23])[cH:16][cH:17][cH:18][cH:19]1.[Cl:33][CH2:34][Cl:35]>>[Br:1][c:2]1[cH:3][c:4]([CH2:7][N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[S:20]([c:15]2[c:14]([Cl:13])[cH:19][cH:18][cH:17][cH:16]2)(=[O:21])=[O:22])[s:5][cH:6]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 761872-Chlorobenzenesulfonyl chloride

HCID 81531Diisopropylethylamine

HCID 28833175[(4-Bromothiophen-2-yl)methyl](2-methylpropyl)amine

Product 1

HCID 67439155N-(4-bromo-thiophen-2-ylmethyl)-2-chloro-N-isobutyl-benzenesulfonamide

Sources & evidence

ORD record: ord-f9ce8db55c9943d4b4435596aa0adf19
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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