Cyclopentanone → Ethyl 3-(cyclopentylamino)-2,2-dimethylpropanoate
Reaction equation
[CH2:1]([O:3][C:4](=[O:10])[C:5]([CH3:9])([CH3:8])[CH2:6][NH2:7])[CH3:2].[C:11]1(=O)[CH2:15][CH2:14][CH2:13][CH2:12]1.C([O-])(=O)C.[Na+].C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>C(Cl)Cl>[CH2:1]([O:3][C:4](=[O:10])[C:5]([CH3:9])([CH3:8])[CH2:6][NH:7][CH:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1)[CH3:2]Participants
6
Procedure
Reaction of 3-amino-2,2-dimethyl-propionic acid ethyl ester with cyclopentanone, sodium acetate and sodium triacetoxyborohydride in DCM gave 3-Cyclopentylamino-2,2-dimethyl-propionic acid ethyl ester
Sources & evidence
- ORD record
- ord-48c90496f5da4b2ab229632f0761e61f
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08563542B2
Reaction notes
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