Acetonitrile → 2-[4-[1-(2-methoxypyrimidin-5-yl)ethylamino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-methylbenzonitrile

HRID 104745

Reaction equation

HRID 104745 reaction equation
[CH3:21][O:22][c:23]1[n:24][cH:25][c:26]([CH:29]([CH3:30])[NH2:31])[cH:27][n:28]1.[CH3:41][C:42]#[N:43].[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][CH2:9][N:10]([c:12]1[c:13]([C:14]#[N:15])[cH:16][c:17]([CH3:20])[cH:18][cH:19]1)[CH2:11]2>>[c:2]1([NH:31][CH:29]([c:26]2[cH:25][n:24][c:23]([O:22][CH3:21])[n:28][cH:27]2)[CH3:30])[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][CH2:9][N:10]([c:12]1[c:13]([C:14]#[N:15])[cH:16][c:17]([CH3:20])[cH:18][cH:19]1)[CH2:11]2

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 81531DiisopropylethylamineHCID 586290231-(2-Methoxypyrimidin-5-yl)ethanamineHCID 598406882-(4-Chloro-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)-5-methylbenzonitrile

Product 1

HCID 1784941792-[4-[1-(2-methoxypyrimidin-5-yl)ethylamino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-methylbenzonitrile

Sources & evidence

ORD record
ord-79c8a56c002a4b4594eb7e191f4c7ca3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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