Water → Tert-butyl 3-[(2,3-difluorophenyl)-(2-methylsulfonyloxyethoxy)methyl]piperidine-1-carboxylate

HRID 105067

Reaction equation

HRID 105067 reaction equation
[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:34][S:35]([Cl:36])(=[O:37])=[O:38].[Cl:40][CH2:41][Cl:42].[F:1][c:2]1[c:3]([CH:9]([CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[O:23][CH2:24][CH2:25][OH:26])[cH:4][cH:5][cH:6][c:7]1[F:8].[OH2:39]>>[F:1][c:2]1[c:3]([CH:9]([CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[O:23][CH2:24][CH2:25][O:26][S:35]([CH3:34])(=[O:37])=[O:38])[cH:4][cH:5][cH:6][c:7]1[F:8]

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 68716185Tert-butyl 3-[(2,3-difluorophenyl)-(2-hydroxyethoxy)methyl]piperidine-1-carboxylate

Product 1

HCID 72529612Tert-butyl 3-[(2,3-difluorophenyl)-(2-methylsulfonyloxyethoxy)methyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-74c195a124e741d68b16ad7d2070914d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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