Thiophenol → HCID 89295434, compound
Reaction equation
[C:1](OC1C=CC(C2C=CC=CC=2)=CC=1)(=[O:4])[C:2]#[CH:3].[C:18]1([SH:24])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.C(O)(=O)C#C.C1CCC(N=C=NC2CCCCC2)CC1>CN(C1C=CN=CC=1)C>[C:1](=[O:4])([S:24][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:2]#[CH:3]Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Procedure
The compound 19 was prepared according to the method described for compound 1 employing thiophenol (1 g, 9.07 mmol), propargylic acid (0.64 g, 9.07 mmol), DCC (1.87 g, 9.07 mmol) and DMAP (7.3 mg, 0.06 mmol) to give brownish liquid compound 19 (1.24 g, 84%). 1H NMR (300 MHz, CD2Cl2) δ 3.40 (s, 1H), 7.46 (s, 5H).
Workup
- customThe compound 19 was prepared
Sources & evidence
- ORD record
- ord-4b0f6e665bed445ba1d4a394b758b5b2
- Source dataset
- uspto-grants-2016_07
- Patent number
- US09393306B2
Reaction notes
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