Phenyl Isothiocyanate → N-phenyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)thiourea

Reaction equation

[NH2:1][c:2]1[cH:3][c:4]2[c:5]([CH:11]3[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH2:16]3)[cH:6][nH:7][c:8]2[cH:9][cH:10]1.[c:18]1([N:24]=[C:25]=[S:26])[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([CH:11]3[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH2:16]3)[cH:6][nH:7][c:8]2[cH:9][cH:10]1)[C:25]([NH:24][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)=[S:26]

Participants

Reactant 2

HCID 7673Phenyl Isothiocyanate

HCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611503N-phenyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)thiourea

Sources & evidence

ORD record: ord-0b13236cbc7d4acd81ec84892b51a996
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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