Ammonia → 3-Amino-4-methoxybenzo[b]thiophene-2-carboxamide

HRID 105559

Reaction equation

HRID 105559 reaction equation
[Li:1].[Li:4].[NH2-:2].[NH2:5][c:6]1[c:7]2[c:8]([s:9][c:10]1[C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16][cH:17][c:18]2[O:19][CH3:20].[NH3:3].[O:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1>>[NH2:2][C:11]([c:10]1[c:6]([NH2:5])[c:7]2[c:8]([s:9]1)[cH:15][cH:16][cH:17][c:18]2[O:19][CH3:20])=[O:12]

Participants

6

Reactant 5

HCID 222AmmoniaHCID 8028TetrahydrofuranHCID 2826723AzanideHCID 3028194Lithium2×HCID 10799875Methyl 3-amino-4-methoxy-1-benzothiophene-2-carboxylate

Product 1

HCID 189637773-Amino-4-methoxybenzo[b]thiophene-2-carboxamide

Sources & evidence

ORD record
ord-6894cde13b274462b494ae05042be61d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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