3-(benzyloxy)-5-bromo-1-(4-butylphenyl)pyridin-4(1H)-one → 3-(benzyloxy)-1-(4-butylphenyl)-5-cyclopropylpyridin-4(1H)-one
Reaction equation
[CH2:1]([O:8][C:9]1[C:14](=[O:15])[C:13](Br)=[CH:12][N:11]([C:17]2[CH:22]=[CH:21][C:20]([CH2:23][CH2:24][CH2:25][CH3:26])=[CH:19][CH:18]=2)[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br-].[CH:28]1([Zn+])[CH2:30][CH2:29]1>C1COCC1>[CH2:1]([O:8][C:9]1[C:14](=[O:15])[C:13]([CH:28]2[CH2:30][CH2:29]2)=[CH:12][N:11]([C:17]2[CH:22]=[CH:21][C:20]([CH2:23][CH2:24][CH2:25][CH3:26])=[CH:19][CH:18]=2)[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
4
Conditions
- Temperature
- 60 °C