Dichloromethane → tert-butyl N-[1-[6-fluoro-2-(2-hydroxyphenyl)quinazolin-4-yl]pyrrolidin-3-yl]carbamate
Reaction equation
[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[Cl:21][c:22]1[n:23][c:24](-[c:33]2[c:34]([OH:39])[cH:35][cH:36][cH:37][cH:38]2)[n:25][c:26]2[cH:27][cH:28][c:29]([F:32])[cH:30][c:31]12.[Cl:40][CH2:41][Cl:42].[NH:1]1[CH2:2][CH:3]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:4][CH2:5]1>>[N:1]1([c:22]2[n:23][c:24](-[c:33]3[c:34]([OH:39])[cH:35][cH:36][cH:37][cH:38]3)[n:25][c:26]3[cH:27][cH:28][c:29]([F:32])[cH:30][c:31]23)[CH2:2][CH:3]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:4][CH2:5]1Participants
5
