Acetic Anhydride → N-(3-bromo-4-methoxyphenyl)acetamide

HRID 1059183

Reaction equation

HRID 1059183 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[O:11][CH3:12].[C:13](OC(=O)C)(=[O:15])[CH3:14]>[Fe]>[Br:1][C:2]1[CH:7]=[C:6]([NH:8][C:13](=[O:15])[CH3:14])[CH:5]=[CH:4][C:3]=1[O:11][CH3:12]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 788702-Bromo-4-nitroanisole

Product 1

HCID 244158N-(3-bromo-4-methoxyphenyl)acetamide

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

By the reaction in the same manner as in Example 33-(i) using 2-bromo-4-nitroanisole (5.41 g), iron powder (6.49 g) and acetic anhydride (4.4 ml), the title compound (4.87 g) was obtained as a colorless powder crystals.

Sources & evidence

ORD record
ord-86b40695a4af4a518e8fd0c57262b5ed
Source dataset
uspto-grants-2003_02
Patent number
US06518257B1

Linked notes

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