(5-(1-Hydroxy-1-methyl-ethyl))-pyridine-2-sulfonic acid amide → 2-Pyridinesulfonamide, 5-(1-methylethenyl)-

HRID 1059706

Reaction equation

HRID 1059706 reaction equation
O[C:2]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[N:9][CH:10]=1)([CH3:4])[CH3:3]>C(C(O)=O)(F)(F)F>[C:2]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[N:9][CH:10]=1)([CH3:4])=[CH2:3]

Participants

3

Reactant 1

HCID 54360667(5-(1-Hydroxy-1-methyl-ethyl))-pyridine-2-sulfonic acid amide

Product 1

HCID 450806412-Pyridinesulfonamide, 5-(1-methylethenyl)-

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

A solution of 0.1 g of (5-(1-hydroxy-1-methyl-ethyl))-pyridine-2-sulfonic acid amide in CF3CO2H (2 ml) was refluxed for 20 h. The solvent was then removed in vacuo to give 5-isopropenyl-pyridine-2-sulfonic acid amide as a white solid which was essentially pure. El mass spectrum, m/e 198 (M calculated for C8H10N2O2S: 198).

Workup

  1. customThe solvent was then removed in vacuo

Sources & evidence

ORD record
ord-8e47057e93b544cfb904eb7f51a2b3b8
Source dataset
uspto-grants-2003_02
Patent number
US06521631B2

Linked notes

Loading…