Acetonitrile → 4-[4-[(5-Methoxy-[1,3]thiazolo[5,4-b]pyridin-2-yl)methyl]piperazin-1-yl]phenol

HRID 106150

Reaction equation

HRID 106150 reaction equation
[CH3:27][C:28]#[N:29].[Cl:1][CH2:2][c:3]1[s:4][c:5]2[n:6][c:7]([O:12][CH3:13])[cH:8][cH:9][c:10]2[n:11]1.[N:14]1([c:20]2[cH:21][cH:22][c:23]([OH:26])[cH:24][cH:25]2)[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]1>>[CH2:2]([c:3]1[s:4][c:5]2[n:6][c:7]([O:12][CH3:13])[cH:8][cH:9][c:10]2[n:11]1)[N:17]1[CH2:16][CH2:15][N:14]([c:20]2[cH:21][cH:22][c:23]([OH:26])[cH:24][cH:25]2)[CH2:19][CH2:18]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 92467p-(1-Piperazinyl)phenolHCID 220659682-(Chloromethyl)-5-methoxy[1,3]thiazolo[5,4-b]pyridine

Product 1

HCID 100211784-[4-[(5-Methoxy-[1,3]thiazolo[5,4-b]pyridin-2-yl)methyl]piperazin-1-yl]phenol

Sources & evidence

ORD record
ord-dd901e7406d24818ae5b7ccff3f6348b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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