Thionyl Chloride → 3-Ethylbenzoyl chloride

HRID 1062644Notes

Reaction equation

HRID 1062644 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6](O)=[O:7])[CH3:2].S(Cl)([Cl:14])=O>CN(C)C=O>[CH2:1]([C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6]([Cl:14])=[O:7])[CH3:2]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 96207Benzoic acid, 3-ethyl-

Product 1

HCID 128093233-Ethylbenzoyl chloride

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Procedure

3-Ethylbenzoic acid (9.40 g, 62.6 mmol) was added slowly to thionyl chloride (45 mL) at 0° C., and N,N-dimethylformamide (3 drops) was added dropwise. The obtained reaction mixture was refluxed under heating as it was for 2 h. The reaction mixture was concentrated and used without purification in the next reaction.

Workup

  1. customThe obtained reaction mixture
  2. temperaturewas refluxed
  3. temperatureunder heating as it
  4. concentrationThe reaction mixture was concentrated
  5. customused without purification in the next reaction

Sources & evidence

ORD record
ord-d2a2341ea8204d60af313ec6cefd3139
Source dataset
uspto-grants-2005_11
Patent number
US06962933B1

Reaction notes

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