Ethanol →

HRID 1063

Reaction equation

HRID 1063 reaction equation
[CH2:1]([OH:3])[CH3:2].C(Cl)(Cl)(Cl)Cl.[Mg:9].[C:10]([O:16]CC)(=[O:15])[CH2:11][C:12]([O-:14])=[O:13].[CH3:19][CH2:20]OCC>>[CH2:19]([C:11]([CH2:1][CH3:2])([C:12]([O-:14])=[O:13])[C:10]([O-:16])=[O:15])[CH3:20].[CH2:1]([O:3][Mg+2:9])[CH3:2]

Participants

5

Reactant 5

HCID 702EthanolHCID 3283Diethyl Ether2×HCID 5943Carbon TetrachlorideHCID 3595298Propanedioic acid, monoethyl esterHCID 5462224Magnesium2×

Product 0

No Product data yet.

Procedure

A mixture of 2.7 ml of ethanol and 0.3 ml of CCl4 is added dropwise to 2.9 g (0.12 mol) of magnesium which has been degreased with ether. 41 ml of anhydrous ether are introduced dropwise, followed by 20 g (0.125 mol) of ethyl malonate, the solvents being kept at the reflux point without heating. When the addition has ended, the mixture is refluxed for 5 h until the magnesium has completely disappeared.

Workup

  1. temperaturewithout heating
  2. additionWhen the addition

Sources & evidence

ORD record
ord-5cf66b8388c64d4ca6458c65853a7f08
Source dataset
uspto-grants-1998_03
Patent number
US05723485

Linked notes

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