Methylamine → HCID 69736456, compound

Reaction equation

[CH3:1][NH2:2].[Cl:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]2[CH:10]=[C:11]([C:13]([O-:15])=O)[S:12][C:5]=12.[Li+]>>[CH3:1][NH:2][C:13]([C:11]1[S:12][C:5]2[C:6](=[N:7][CH:8]=[CH:9][C:4]=2[Cl:3])[CH:10]=1)=[O:15]

Participants

Reactant 2

HCID 6329Methylamine

HCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 69736456HCID 69736456, compound

Procedure

The title compound was prepared from methylamine and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: n.d.; HPLC Rf: 3.70 min.; HPLC purity: 89%.

Sources & evidence

ORD record: ord-063f1676e7644b7a9eca370311134a1c
Source dataset: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06964961B2

Reaction notes

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