Hydrogen Peroxide → 4-Methyl-6-[4-(2-quinolylsulfinyl)-butoxy]-carbostyril

Reaction equation

[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][S:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)[CH:10]=2)[NH:5][C:4](=[O:28])[CH:3]=1.[OH:29]O>>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][S:17]([C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[O:29])[CH:10]=2)[NH:5][C:4](=[O:28])[CH:3]=1

Participants

Reactant 2

HCID 784Hydrogen Peroxide

HCID 205400764-Methyl-6-[4-(2-quinolyl-mercapto)-butoxy]-carbostyril

Product 1

HCID 205400004-Methyl-6-[4-(2-quinolylsulfinyl)-butoxy]-carbostyril

Procedure

Prepared analogous to Example 123 from 4-methyl-6-[4-(2-quinolyl-mercapto)-butoxy]-carbostyril and hydrogen peroxide.

Sources & evidence

ORD record: ord-fa64ef257ba541198968c536281c3c4d
Source dataset: uspto-grants-1982_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04329347

Reaction notes

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