Imidazole → 2-[(Tert-butyldimethylsilyl)oxy]-5-chloroaniline

HRID 106609

Reaction equation

[C:10]([CH3:11])([CH3:12])([CH3:13])[Si:14]([CH3:15])([CH3:16])[Cl:17].[NH2:1][c:2]1[c:3]([OH:9])[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[O:23]=[CH:24][N:25]([CH3:26])[CH3:27].[nH:18]1[cH:19][cH:20][n:21][cH:22]1>>[NH2:1][c:2]1[c:3]([O:9][Si:14]([C:10]([CH3:11])([CH3:12])[CH3:13])([CH3:15])[CH3:16])[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

Reactant 4

HCID 795Imidazole

HCID 6228Dimethylformamide

HCID 72652-Amino-4-chlorophenol

HCID 28928tert-Butyldimethylsilyl chloride

Product 1

HCID 695922282-[(Tert-butyldimethylsilyl)oxy]-5-chloroaniline

Sources & evidence

ORD record: ord-4bd7b2829abc45ee8aa7b0053f7e11d8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Linked notes

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