Bromoacetonitrile → 2-(2-Oxothiazolidin-3-yl)acetonitrile

HRID 1070381

Reaction equation

HRID 1070381 reaction equation
Br[CH2:2][C:3]#[N:4].[S:5]1[CH2:9][CH2:8][NH:7][C:6]1=[O:10]>CN(C=O)C>[O:10]=[C:6]1[N:7]([CH2:2][C:3]#[N:4])[CH2:8][CH2:9][S:5]1

Participants

4

Reactant 2

HCID 11534BromoacetonitrileHCID 974312-Thiazolidinone

Product 1

HCID 223965392-(2-Oxothiazolidin-3-yl)acetonitrile

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Preparation took place in analogy to Example IV a from bromoacetonitrile and 2-thiazolidinone. The substance was employed as DMF-containing crude product in the next reaction.

Workup

  1. customPreparation
  2. additioncontaining crude product
  3. customin the next reaction

Sources & evidence

ORD record
ord-55aac4ac3c8c457e927514a79cb8a3c1
Source dataset
uspto-grants-2005_06
Patent number
US06903089B1

Linked notes

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