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Hydrochloric Acid → Tert-butyl 4-(1-hydroxy-2-pyrrolidin-1-ylethyl)piperidinecarboxylate

HRID 107269
Notes
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Reaction equation

HRID 107269 reaction equation
[BH4-:22].[CH3:25][OH:26].[ClH:24].[N:1]1([CH2:6][C:7](=[O:8])[CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Na+:23]>>[N:1]1([CH2:6][CH:7]([OH:8])[CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1
ParticipantsSources & evidenceReaction notes

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium IonHCID 28123BorohydrideHCID 23079654Tert-butyl 4-(2-pyrrolidin-1-ylacetyl)piperidinecarboxylate

Product 1

HCID 23079661Tert-butyl 4-(1-hydroxy-2-pyrrolidin-1-ylethyl)piperidinecarboxylate

Sources & evidence

ORD record
ord-2f3cec4f4ff14f9b9f62979cd5139108
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes