Sodium hydride → HCID 14988300, compound

Reaction equation

[N:1]1[CH:6]=[CH:5][C:4]([NH:7][N:8]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH:10]=[CH:9]2)=[CH:3][CH:2]=1.[CH3:17][N:18]([CH2:20][CH2:21][CH2:22]Cl)[CH3:19].[H-].[Na+]>>[CH3:17][N:18]([CH2:20][CH2:21][CH2:22][N:7]([C:4]1[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=1)[N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:10]=[CH:9]1)[CH3:19]

Participants

Reactant 3

HCID 24758Sodium hydride

HCID 669603-Chloro-N,N-dimethyl-1-propanamine

HCID 3081186N-(4-pyridinyl)-1H-indol-1-amine

Product 1

HCID 14988300HCID 14988300, compound

Procedure

The title compound was prepared from N-(4-pyridinyl)-1H-indol-1-amine and dimethylaminopropyl chloride with the aid of NaH in substantially the same manner as in Example 4. The product was obtained as an oil.

Workup

customThe product was obtained as an oil

Sources & evidence

ORD record: ord-730c8faaf4ad4919b3d114cecf123181
Source dataset: uspto-grants-1990_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04970218

Reaction notes

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