Hydrochloric Acid → 2-[(4-Nitrophenyl)thio]-1-phenyl-1H-imidazole hydrochloride
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[N:12]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:13]=[CH:14][N:15]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[ClH:22]>>[ClH:22].[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[N:12]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:13]=[CH:14][N:15]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]Participants
3
Procedure
The product from Example 24 was converted to the hydrochloride salt by treatment with ethanolic hydrogen chloride. After recrystallization from methanol/isopropanol/ether the product was obtained off-white prisms, mp 215°-218° C.
Workup
- customAfter recrystallization from methanol/isopropanol/ether the product
- customwas obtained off-white prisms, mp 215°-218° C.
Sources & evidence
- ORD record