Methanol → HCID 85711145, compound

HRID 1075408

Reaction equation

HRID 1075408 reaction equation
[CH2:1]([N:11]([CH3:22])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[Br:23][CH2:24][CH2:25][CH2:26][Cl:27].CO>CCCCCC>[Br-:23].[Cl:27][CH2:26][CH2:25][CH2:24][N+:11]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH3:22]

Participants

5

Reactant 3

HCID 887MethanolHCID 80061-Bromo-3-chloropropaneHCID 818801-Decanamine, N-decyl-N-methyl-

Product 1

HCID 85711145HCID 85711145, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Conditions

Temperature
65 °C

Procedure

A two-liter, 3-necked, round-bottomed flask equipped with air condensers and a magnetic stirring plate was charged with N,N-didecylmethylamine (65.49 grams, 0.21 moles), 1-bromo-3-chloropropane (33.06 grams, 0.21 moles) and methanol (250 mL). Reaction was maintained at 65° C. for six days. Methanol was removed by rotary evaporation under reduced pressure to yield an oil. To the oil was added hexane (200 mL) causing a white solid to slowly form. The solvent was decanted off from the mixture. The remaining solid dried overnight under vacuum. Yield 81.67 grams 0.17 moles, 82%).

Workup

  1. customA two-liter, 3-necked, round-bottomed flask equipped with air condensers
  2. customReaction
  3. customMethanol was removed by rotary evaporation under reduced pressure
  4. customto yield an oil
  5. customto slowly form
  6. customThe solvent was decanted off from the mixture
  7. customThe remaining solid dried overnight under vacuum

Sources & evidence

ORD record
ord-6c47187198bf456ea18d2bb4b962af41
Source dataset
uspto-grants-1999_05
Patent number
US05900475

Linked notes

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