Dimethyl Sulfoxide → 2-(4-Amino-2-oxopyridin-1(2H)-yl)-N-benzyl-4-methylthiazole-5-carboxamide

HRID 107843

Reaction equation

HRID 107843 reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:17])[n:13][c:14]([Br:16])[s:15]1.[CH3:43][S:44](=[O:45])[CH3:46].[Cu:47][I:48].[K+:30].[K+:31].[NH2:18][c:19]1[cH:20][c:21](=[O:25])[nH:22][cH:23][cH:24]1.[OH2:49].[OH:32][c:33]1[cH:34][cH:35][cH:36][c:37]2[c:38]1[n:39][cH:40][cH:41][cH:42]2>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:17])[n:13][c:14](-[n:22]2[c:21](=[O:25])[cH:20][c:19]([NH2:18])[cH:24][cH:23]2)[s:15]1

Participants

9

Reactant 8

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 19238-HydroxyquinolineHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 5735304-Amino-1,2-dihydropyridin-2-oneHCID 579593962-Bromo-4-methyl-thiazole-5-carboxylic acid benzylamide

Product 1

HCID 249852702-(4-Amino-2-oxopyridin-1(2H)-yl)-N-benzyl-4-methylthiazole-5-carboxamide

Sources & evidence

ORD record
ord-dd73141206754ead925d43a6b9197e67
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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