Dimethylformamide → 5-Fluoro-2-(2,2,2-trifluoroethoxy)nitrobenzene

Reaction equation

[C:12](=[O:13])([O-:14])[O-:15].[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[Cs+:16].[Cs+:17].[F:1][c:2]1[cH:3][c:4]([N+:9](=[O:10])[O-:11])[c:5]([OH:8])[cH:6][cH:7]1.[c:18]1([CH3:19])[cH:20][cH:21][c:22]([S:23]([O:24][CH2:28][C:29]([F:30])([F:31])[F:32])(=[O:25])=[O:26])[cH:27][cH:33]1>>[F:1][c:2]1[cH:3][c:4]([N+:9](=[O:10])[O-:11])[c:5]([O:8][CH2:28][C:29]([F:30])([F:31])[F:32])[cH:6][cH:7]1

Participants

Reactant 5

HCID 6228Dimethylformamide

HCID 19660Carbonate Ion

HCID 67942Ethanol, 2,2,2-trifluoro-, 1-(4-methylbenzenesulfonate)

HCID 104967Cesium cation2×

HCID 1362364-Fluoro-2-nitrophenol

Product 1

HCID 234479215-Fluoro-2-(2,2,2-trifluoroethoxy)nitrobenzene

Sources & evidence

ORD record: ord-9c1d8885270d4ae98575eb5bb7f41a77
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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