Dimethylformamide → 2-Chloro-4-[4-(3-chloro-phenylethynyl)-2-methyl-imidazol-1-yl]-pyridine

Reaction equation

[C:24](=[O:25])([O-:26])[O-:27].[Cl:16][c:17]1[n:18][cH:19][cH:20][c:21]([F:23])[cH:22]1.[Cl:1][c:2]1[cH:3][c:4]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:15])[nH:13][cH:14]2)[cH:5][cH:6][cH:7]1.[Cs+:28].[Cs+:29].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[Cl:1][c:2]1[cH:3][c:4]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:15])[n:13](-[c:21]3[cH:20][cH:19][n:18][c:17]([Cl:16])[cH:22]3)[cH:14]2)[cH:5][cH:6][cH:7]1

Participants

Reactant 5

HCID 6228Dimethylformamide

HCID 19660Carbonate Ion

HCID 104967Cesium cation2×

HCID 27827922-Chloro-4-fluoropyridine

HCID 178432693HCID 178432693, compound

Product 1

HCID 866498792-Chloro-4-[4-(3-chloro-phenylethynyl)-2-methyl-imidazol-1-yl]-pyridine

Sources & evidence

ORD record: ord-9ed1ff08d723450db55850b52398de6e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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