Diethyl Ether → 2-[2-amino-6-(2,6-dichlorophenyl)-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-8-yl]acetic acid

HRID 108435

Reaction equation

HRID 108435 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[c:9](=[O:27])[c:10](-[c:19]2[c:20]([Cl:26])[cH:21][cH:22][cH:23][c:24]2[Cl:25])[cH:11][c:12]2[c:13]1[n:14][c:15]([NH2:18])[n:16][cH:17]2)=[O:28].[CH2:41]([Cl:42])[Cl:43].[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[O:5]=[C:6]([CH2:7][n:8]1[c:9](=[O:27])[c:10](-[c:19]2[c:20]([Cl:26])[cH:21][cH:22][cH:23][c:24]2[Cl:25])[cH:11][c:12]2[c:13]1[n:14][c:15]([NH2:18])[n:16][cH:17]2)[OH:28]

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 5328630tert-butyl 2-[2-amino-6-(2,6-dichlorophenyl)-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-8-yl]acetate

Product 1

HCID 53286312-[2-amino-6-(2,6-dichlorophenyl)-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-8-yl]acetic acid

Sources & evidence

ORD record
ord-1640a4e2b62e4564ae0b8b903017cd72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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