[C:1]1(=[O:7])[O:6][C:4](=O)[CH:3]=[CH:2]1.C1(C)C=CC=CC=1.[OH:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]([C:25]2[CH:30]=[CH:29][C:28]([NH2:31])=[CH:27][CH:26]=2)([CH3:24])[CH3:23])=[CH:18][CH:17]=1.C(O)(C)C>S(=O)(=O)(O)O.O>[OH:15][C:16]1[CH:17]=[CH:18][C:19]([C:22]([C:25]2[CH:26]=[CH:27][C:28]([N:31]3[C:1](=[O:7])[CH:2]=[CH:3][C:4]3=[O:6])=[CH:29][CH:30]=2)([CH3:24])[CH3:23])=[CH:20][CH:21]=1To a reaction vessel equipped with a stirrer, thermometer and an azeotropic distillation trap, 60 g (0.1 mole) of maleic anhydride, 480 g of toluene and 2.6 g of 95% sulfuric acid were charged and heated to a reflux temperature. A solution containing 114 g (0.5 mole) of 2-(4-hydroxyphenyl)-2-(4-aminophenyl)propane in 160 g of N,N'-dimethylacetamide was dropwise added from a dropping funnel over 4 to 5 hours and reacted for 5 hours at the same temperature. Generated water by the reaction was removed by azeotropic distillation. After completing the reaction, the reaction mixture was cooled to 80° to 90° C. and the solvent was successively removed under reduced pressure. The organic layer thus obtained was mixed with 100 ml of isopropyl alcohol and then 300 ml of water was added and stirred for 0.5 to 1 hour to precipitate crystals. The crystals were filtered and dried to obtain 147 g of 2-(4-hydroxyphenyl)-2-(4-maleimidophenyl)propane as yellow crystals. The yield was 96%.
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