Hydroxide → 1-(3-Chloro-1,2,4-thiadiazol-5-yl)-4-[2-(trifluoromethyl)phenyl]sulfonylpyrrolidine-2-carboxylic acid

Reaction equation

[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([c:23]2[n:24][c:25]([Cl:28])[n:26][s:27]2)[CH2:7][CH:8]([S:10](=[O:11])(=[O:12])[c:13]2[c:14]([C:19]([F:20])([F:21])[F:22])[cH:15][cH:16][cH:17][cH:18]2)[CH2:9]1.[Li+:29].[OH-:30]>>[O:2]=[C:3]([OH:4])[CH:5]1[N:6]([c:23]2[n:24][c:25]([Cl:28])[n:26][s:27]2)[CH2:7][CH:8]([S:10](=[O:11])(=[O:12])[c:13]2[c:14]([C:19]([F:20])([F:21])[F:22])[cH:15][cH:16][cH:17][cH:18]2)[CH2:9]1

Participants

Reactant 3

HCID 961Hydroxide

HCID 28486Lithium ion

HCID 178498644HCID 178498644, compound

Product 1

HCID 772300081-(3-Chloro-1,2,4-thiadiazol-5-yl)-4-[2-(trifluoromethyl)phenyl]sulfonylpyrrolidine-2-carboxylic acid

Sources & evidence

ORD record: ord-cbde210a021b4550a18a41ddc34ad4f7
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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