Dichloromethane → 4-[3-(6-Ethyl-pyridin-3-yl)-phenyl]-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Reaction equation

[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:18][C:19]([CH2:20][C:21](=[O:5])[c:23]2[cH:24][c:25](-[c:29]3[cH:30][n:31][c:32]([CH2:35][CH3:36])[cH:33][cH:34]3)[cH:26][cH:27][cH:28]2)=[O:37])[cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1)([CH3:6])([CH3:22])[CH3:38].[Cl:46][CH2:47][Cl:48].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[N:7]1=[C:21]([c:23]2[cH:24][c:25](-[c:29]3[cH:30][n:31][c:32]([CH2:35][CH3:36])[cH:33][cH:34]3)[cH:26][cH:27][cH:28]2)[CH2:20][C:19](=[O:37])[NH:18][c:9]2[c:8]1[cH:13][cH:12][c:11]([C:14]([F:15])([F:16])[F:17])[cH:10]2