Diethyl Ether → 1-(2-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

HRID 109654

Reaction equation

HRID 109654 reaction equation
[CH3:12][O:13][c:14]1[c:15]([C:20]2=[N:21][CH2:22][CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][c:29]32)[cH:16][cH:17][cH:18][cH:19]1.[CH3:37][CH2:38][O:39][CH2:40][CH3:41].[NH2:1][CH:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7][cH:8]2)[CH2:9][CH:10]1[OH:11].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[CH3:12][O:13][c:14]1[c:15]([CH:20]2[NH:21][CH2:22][CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][c:29]32)[cH:16][cH:17][cH:18][cH:19]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 6422Trifluoroacetic acidHCID 1390341-Amino-2-indanolHCID 675387781-(2-Methoxyphenyl)-3,4-dihydroisoquinoline

Product 1

HCID 242573611-(2-Methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-543ae29145994a5f9717e8941b72c482
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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