Dichloromethane → 1-[1-(4-Methoxy-2,3-dimethyl-phenyl)-ethyl]-piperazine

Reaction equation

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([CH:14]([CH3:15])[c:16]2[c:17]([CH3:25])[c:18]([CH3:24])[c:19]([O:22][CH3:23])[cH:20][cH:21]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[NH:8]1[CH2:9][CH2:10][N:11]([CH:14]([CH3:15])[c:16]2[c:17]([CH3:25])[c:18]([CH3:24])[c:19]([O:22][CH3:23])[cH:20][cH:21]2)[CH2:12][CH2:13]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 691567024-[1-(4-Methoxy-2,3-dimethyl-phenyl)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 220219311-[1-(4-Methoxy-2,3-dimethyl-phenyl)-ethyl]-piperazine

Sources & evidence

ORD record: ord-713f306d7d74453da1f1b8b05dc545bd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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