Potassium Cation → 1-[2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4-piperidinecarbonitrile

HRID 109815

Reaction equation

[CH3:1][c:2]1[n:3][nH:4][c:5]([C:7]([F:8])([F:9])[F:10])[cH:6]1.[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[Cl:13][CH2:14][C:15](=[O:16])[N:17]1[CH2:18][CH2:19][CH:20]([C:23]#[N:24])[CH2:21][CH2:22]1.[K+:12].[OH-:11].[OH2:30]>>[CH3:1][c:2]1[n:3]([CH2:14][C:15](=[O:16])[N:17]2[CH2:18][CH2:19][CH:20]([C:23]#[N:24])[CH2:21][CH2:22]2)[n:4][c:5]([C:7]([F:8])([F:9])[F:10])[cH:6]1

Participants

Reactant 6

HCID 813Potassium Cation

HCID 961Hydroxide

HCID 962Water

HCID 6228Dimethylformamide

HCID 1390771H-Pyrazole, 3-methyl-5-(trifluoromethyl)-

HCID 674700971-(2-Chloroacetyl)piperidine-4-carbonitrile

Product 1

HCID 674706371-[2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4-piperidinecarbonitrile

Sources & evidence

ORD record: ord-f66739bc558b4edeb028fabc7ed4782f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Linked notes

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