Tetrahydrofuran → N-{3-[3-(2-chloro-4-pyrimidinyl)-6-methylpyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide

HRID 109831

Reaction equation

HRID 109831 reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:18]3[cH:19][c:20]([NH2:24])[cH:21][cH:22][cH:23]3)[n:10][n:11]3[c:12]2[cH:13][cH:14][c:15]([CH3:17])[cH:16]3)[n:7]1.[s:25]1[c:26]([CH2:30][C:31](=[O:32])[Cl:33])[cH:27][cH:28][cH:29]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:18]3[cH:19][c:20]([NH:24][C:31]([CH2:30][c:26]4[s:25][cH:29][cH:28][cH:27]4)=[O:32])[cH:21][cH:22][cH:23]3)[n:10][n:11]3[c:12]2[cH:13][cH:14][c:15]([CH3:17])[cH:16]3)[n:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 1623622-Thiopheneacetyl chlorideHCID 57737218{3-[3-(2-Chloro-4-pyrimidinyl)-6-methylpyrazolo[1,5-a]pyridin-2-yl]phenyl}amine

Product 1

HCID 57737227N-{3-[3-(2-chloro-4-pyrimidinyl)-6-methylpyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide

Sources & evidence

ORD record
ord-5270b67ef51147a9b7fbd0116f47f9e6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…